In this review, we provide a brief synopsis of the connections between adipose tissue and metabolic health and highlight some recent developments in understanding and exploiting adipocyte biology.Adipose tissue plays critical roles in the regulation of systemic glucose and lipid metabolism and secretes bioactive molecules VITAMIN D3 possessing endo
Over the past several years, global project management teams have been facing dynamic challenges that continue to grow exponentially with the increasing number of complexities associated with the undertaken tasks.The ever-evolving organizational challenges demand project managers to adapt novel management practices to accomplish organizational goal
Escape from chemotherapy-induced apoptosis is a hallmark of drug resistance in cancer.The recent identification of alternative programmed cell death pathways opens up for possibilities to circumvent the apoptotic blockade in drug resistant cancer and eliminate malignant cells.Indeed, we have Henry Blooms recently shown that programmed necrosis, ter
It is rare for HTR Circuit Board IgM multiple myeloma (MM) and mantle cell lymphoma (MCL) to coexist.Furthermore, it is challenging to demonstrate if there are two distinct types of neoplasia or if plasma cell differentiation of MCL is present.We discuss the case of a patient concomitantly diagnosed with MCL and IgM MM, and the subsequent diagnosti
Physical exercise stimulates organs, mainly the skeletal muscle, to release a broad range of molecules, recently dubbed exerkines.Among them, RNAs, such as miRNAs, piRNAs, and tRNAs loaded in extracellular vesicles (EVs) have the potential to play a significant role in the way muscle and other organs communicate KItchen Bin to translate exercise in